Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763213 | 0.84 | KMT2A (0.46) | HSD17B10NPC1LMNAGAATDP1 | |
| SCHEMBL28034022 | 0.76 | NPC1 (0.50) | HSD17B10NPC1LMNASMN1; SMN2MEN1 | |
| SCHEMBL27894210 | 0.76 | TSHR (0.53) | KDM4EHSD17B10NPC1LMNAGAA | |
| SCHEMBL9360777 | 0.76 | PARP1 (0.47) | NPC1GAATDP1SMN1; SMN2RAB9A | |
| SCHEMBL29702037 | 0.75 | TSHR (0.63) | KDM4EHSD17B10NPC1LMNAKMT2A | |
| SCHEMBL101601 | 0.75 | TSHR (0.63) | KDM4EHSD17B10NPC1LMNAKMT2A | |
| SCHEMBL24233351 | 0.74 | ERCC5 (0.55) | KDM4EHSD17B10NPC1LMNAMEN1 | |
| SCHEMBL27488418 | 0.74 | MEN1 (0.49) | KDM4ENPC1LMNASMN1; SMN2MEN1 | |
| Hydrazine SCHEMBL27689332 | 0.74 | ALDH1A1 (0.60) | KDM4EHSD17B10NPC1LMNAGAA | |
| SCHEMBL28748022 | 0.74 | ALDH1A1 (0.66) | NPC1SMN1; SMN2KMT2ARAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412529-B1 | Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same | NIPPON CHEMIPHAR CO (JP) | 1994-03-09 | — | — | EP | disclosed |
| US-5091403-A | SULFINYL IMIDAZOLE DERIVATIVES AND ANTIULCER AGENTS CONTAINING THE SAME | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |
| EP-0412529-A1 | Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-02-13 | — | — | EP | disclosed |