Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9361076 | 0.84 | KDM4E (0.50) | KMT2ANPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL27894210 | 0.82 | TSHR (0.53) | KMT2ANPC1RAB9AALDH1A1POLB | |
| SCHEMBL29036935 | 0.81 | CTSD (0.57) | KMT2ANPC1RAB9AALDH1A1TSHR | |
| SCHEMBL28034022 | 0.79 | NPC1 (0.50) | KMT2ANPC1RAB9AALDH1A1POLB | |
| SCHEMBL28770702 | 0.77 | ALDH1A1 (0.61) | KMT2ANPC1RAB9AALDH1A1POLB | |
| SCHEMBL27488418 | 0.77 | MEN1 (0.49) | KMT2ANPC1RAB9APOLBTSHR | |
| SCHEMBL28748022 | 0.77 | ALDH1A1 (0.66) | KMT2ANPC1RAB9AALDH1A1POLB | |
| SCHEMBL27351517 | 0.76 | HPGD (0.53) | KMT2ANPC1RAB9AALDH1A1POLB | |
| SCHEMBL777261 | 0.76 | NPC1 (0.53) | KMT2ANPC1RAB9AL3MBTL1TSHR | |
| SCHEMBL29436920 | 0.76 | NPC1 (0.53) | KMT2ANPC1RAB9AL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100510-A2 | COMBINED PREPARATION OF ANTI-INFECTIOUSLY ACTIVE COMPOUNDS WHICH INHIBIT THE 2-C-METHYLERYTHROSE-4 METABOLIC PATHWAY, AND INHIBITORS OF LIPID METABOLISM | Jomaa, Hassan (DE) | 2001-05-23 | — | — | EP | disclosed |
| WO-1999066875-A2 | COMBINED PREPARATION OF ANTI-INFECTIOUSLY ACTIVE COMPOUNDS WHICH INHIBIT THE 2-C-METHYLERYTHROSE-4 METABOLIC PATHWAY, AND INHIBITORS OF LIPID METABOLISM | JOMAA HASSAN (DE) | 1999-12-29 | — | — | WO | disclosed |