Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.61 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.61 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.61 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | PLK1 | P53350 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503292 | 0.83 | PLK1 (0.65) | MAPTTP53HDAC1HDAC8HDAC6 | |
| SCHEMBL9502439 | 0.82 | MAPT (0.62) | MAPTTP53HDAC1HDAC8HDAC6 | |
| SCHEMBL9366141 | 0.81 | SMN1; SMN2 (0.57) | MAPTTP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9361069 | 0.81 | HDAC1 (0.54) | MAPTTP53SMN1; SMN2LMNANPC1 | |
| SCHEMBL9365181 | 0.81 | ACAT1 (0.73) | MAPTTP53HDAC1HDAC8HDAC6 | |
| SCHEMBL9361276 | 0.81 | ACAT1 (0.67) | MAPTTP53HDAC1HDAC8HDAC6 | |
| SCHEMBL9365091 | 0.81 | ACAT1 (0.70) | MAPTTP53NPC1RAB9AHDAC1 | |
| SCHEMBL9362439 | 0.81 | ACAT1 (0.73) | MAPTTP53HDAC1HDAC8HDAC6 | |
| SCHEMBL9361404 | 0.81 | ACAT1 (0.70) | MAPTTP53NPC1RAB9AHDAC1 | |
| SCHEMBL9362298 | 0.81 | ACAT1 (0.73) | MAPTTP53HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424194-B1 | Benzanilide derivatives and their use as anti-atherosclerotic agents | RHONE POULENC SANTE (FR) | 1994-08-31 | — | — | EP | disclosed |
| US-5159114-A | Anticholesterol agents | RHONE-POULENC SANTE (FR) | 1992-10-27 | — | — | US | disclosed |
| EP-0424194-A2 | Benzanilide derivatives and their use as anti-atherosclerotic agents | RHONE-POULENC SANTE (FR) | 1991-04-24 | — | — | EP | disclosed |