Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745289 | 0.86 | GAA (0.66) | GAAMAPTALDH1A1PPARGAPP | |
| SCHEMBL9362452 | 0.81 | MAPT (0.57) | GAAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL9362990 | 0.81 | RNF4 (0.45) | GAAMAPTALDH1A1KDM4ENPSR1 | |
| SCHEMBL9365774 | 0.79 | RHOC (0.49) | GAAMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL11115002 | 0.79 | GAA (0.70) | GAAMAPTALDH1A1PPARGAPP | |
| SCHEMBL9362324 | 0.79 | MAPT (0.39) | MAPTALDH1A1 | |
| SCHEMBL5309192 | 0.79 | GAA (0.70) | GAAMAPTALDH1A1PPARGAPP | |
| SCHEMBL1030950 | 0.78 | GAA (1.00) | GAAMAPTALDH1A1PPARGAPP | |
| SCHEMBL2097210 | 0.77 | GAA (0.73) | GAAMAPTALDH1A1PPARGAPP | |
| SCHEMBL11331749 | 0.75 | GAA (0.70) | GAAMAPTALDH1A1PPARGAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413666-B1 | Butyric acid derivatives | CIBA GEIGY AG (CH) | 1994-04-13 | — | — | EP | claimed |