Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 12/20 | 0.61 |
| ▸ | HTR7 | P34969 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9365612 | 0.99 | HTR1A (0.60) | HTR1AHTR7DRD2DRD3HTR2A | |
| Hydrochloric Acid SCHEMBL9545427 | 0.98 | HTR1A (0.61) | HTR1AHTR7DRD2DRD3HTR2A | |
| Hydrochloric Acid SCHEMBL9361660 | 0.97 | HTR1A (0.60) | HTR1AHTR7DRD2HTR2AHTR6 | |
| Acetic Acid SCHEMBL9361625 | 0.94 | HTR1A (0.57) | HTR1AHTR7DRD2DRD3HTR2A | |
| Acetic Acid SCHEMBL9362577 | 0.93 | HTR1A (0.58) | HTR1AHTR7DRD2DRD3HTR2A | |
| Acetic Acid SCHEMBL9362124 | 0.93 | HTR1A (0.58) | HTR1AHTR7DRD2DRD3HTR2A | |
| SCHEMBL9545540 | 0.89 | MAPK1 (0.66) | HTR1AHTR7DRD2DRD3HTR2A | |
| Hydrochloric Acid SCHEMBL9545456 | 0.88 | HTR1A (0.49) | HTR1AHTR7DRD2HTR2AHTR6 | |
| SCHEMBL7055346 | 0.87 | HTR1A (0.61) | HTR1AHTR7DRD2DRD3HTR2A | |
| SCHEMBL9362187 | 0.83 | SIRT6 (0.59) | HTR1AHTR7DRD2HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594813-A1 | NOVEL AMIDOALKYL- AND IMIDOALKYL-PIPERAZINES | Astra Aktiebolag (SE) | 1994-05-04 | — | — | EP | disclosed |
| WO-1993021179-A1 | NOVEL AMIDOALKYL- AND IMIDOALKYL-PIPERAZINES | AKTIEBOLAGET ASTRA (SE) | 1993-10-28 | — | — | WO | disclosed |