Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | DDO | Q99489 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30648021 | 1.00 | CA2 (0.50) | CA2TYRFLT3KDM4EALDH1A1 | |
| SCHEMBL27765641 | 0.84 | FGFR1 (0.50) | CDK5CDK5R1MEN1KMT2A | |
| SCHEMBL12348 | 0.83 | CYP2A6 (0.59) | CA2FLT3KDM4EALDH1A1GAA | |
| Fluoride SCHEMBL28393975 | 0.81 | CYP2A6 (0.57) | CA2FLT3KDM4EALDH1A1GAA | |
| SCHEMBL3705264 | 0.78 | TYR (0.47) | CA2TYRFLT3KDM4EALDH1A1 | |
| SCHEMBL30807019 | 0.77 | DAO (0.55) | FLT3KDM4EALDH1A1GAACYP2A6 | |
| SCHEMBL890079 | 0.77 | DAO (0.55) | FLT3KDM4EALDH1A1GAACYP2A6 | |
| SCHEMBL29450050 | 0.77 | CA2 (0.53) | CA2TYRFLT3KDM4EALDH1A1 | |
| SCHEMBL15902150 | 0.77 | CA2 (0.53) | CA2TYRFLT3KDM4EALDH1A1 | |
| SCHEMBL1038241 | 0.76 | BRD4 (0.59) | CA2TYRFLT3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428514-B1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, a tertiary paraphenylenediamine and a benzomorpholine coupler; method and use | OREAL (FR) | 2007-09-19 | — | — | EP | claimed |
| US-20040205903-A1 | Dyeing composition comprising a cationic pyrrolidine-based para-phenylenefiamine, a tertiary para-phenylenediamine and a benzomorpholine coupler, methods and uses | L'OREAL (FR) | 2004-10-21 | — | — | US | claimed |
| US-5785717-A | Composition for the oxidation dyeing of keratin fibers, comprising a diaminopyrazole derivative and a heterocyclic coupler, and dyeing process | L'OREAL (FR) | 1998-07-28 | — | — | US | claimed |
| EP-0446132-B1 | Keratinous fibres dyeing process with 6 or 7-monohydroxyindols at acidic pH and compositions | OREAL (FR) | 1994-09-14 | — | — | EP | claimed |
| US-5279620-A | Containg paraphenylenediamine, para-aminophenol and paraheterocyclic precursors | L'OREAL (FR) | 1994-01-18 | — | — | US | claimed |
| EP-0446132-A1 | Keratinous fibres dyeing process with 6 or 7-monohydroxyindols at acidic pH and compositions | L'OREAL (FR) | 1991-09-11 | — | — | EP | claimed |
| US-5034015-A | Fade resistant hair dyes with better coloring ability | L'OREAL (FR) | 1991-07-23 | — | — | US | claimed |
| EP-0360638-A1 | Process for dyeing keratinous fibres with an indole derivative associated with a nitrite, and composition therefor | L'OREAL (FR) | 1990-03-28 | — | — | EP | claimed |
| EP-3113753-B2 | AQUEOUS OXIDIZING COMPOSITION FOR HAIR | KAO GERMANY GMBH (DE) | 2026-03-18 | — | — | EP | disclosed |
| US-20250263760-A1 | MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2025-08-21 | — | — | US | disclosed |
| US-12319946-B2 | Methods for producing modified bacteria for production of nitroaromatics | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2025-06-03 | — | — | US | disclosed |
| CN-119677717-A | Indolazine derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2025-03-21 | — | — | CN | disclosed |
| US-20240229090-A1 | MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-07-11 | — | — | US | disclosed |
| US-20240229090-A1 | MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-07-11 | — | — | US | disclosed |
| EP-0360638-A1 | Process for dyeing keratinous fibres with an indole derivative associated with a nitrite, and composition therefor | L'OREAL (FR) | 1990-03-28 | — | — | EP | disclosed |
| US-4885295-A | ANALGESICS; ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES | STERLING DRUG INC. (US) | 1989-12-05 | — | — | US | disclosed |
| US-RE32761-E | ANALGESICS, ANTIRHEUMATIC AND ANTIINFLAMMATORY AGENT | STERLING DRUG INC. (US) | 1988-10-04 | — | — | US | disclosed |
| US-4634776-A | ANALGESIC, ANTIRHEUMATIC, ANTIINFLAMMATORY | STERLING DRUG, INC. (US) | 1987-01-06 | — | — | US | disclosed |
| US-4581354-A | ANALGESICS;ANTI-RHEUMATIC AND ANTI-INFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1986-04-08 | — | — | US | disclosed |
| EP-0171037-A2 | 3-Carbonyl-1-aminoalkyl-1H-indoles useful as analgesics and preparation thereof | STERLING WINTHROP INC. (US) | 1986-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040205903-A1 | Dyeing composition comprising a cationic pyrrolidine-based para-phenylenefiamine, a tertiary para-phenylenediamine and a benzomorpholine coupler, methods and uses | CDC73, KRT18, PAH | CA2 1920/4885TYR 10/4885FLT3 3263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.