Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LIG1 | P18858 | 2/20 | 0.43 |
| ▸ | LIG3 | P49916 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5523145 | 0.90 | GLO1 (0.52) | GLO1ERN1MAPTKMT2AALDH1A1 | |
| SCHEMBL5523152 | 0.90 | GLO1 (0.52) | GLO1ERN1MAPTKMT2AALDH1A1 | |
| SCHEMBL12992273 | 0.85 | GLO1 (0.52) | GLO1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL14384272 | 0.82 | GLO1 (0.50) | GLO1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL9358684 | 0.81 | ERN1 (0.59) | ERN1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL9358680 | 0.81 | ERN1 (0.59) | ERN1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL3034223 | 0.80 | GLO1 (0.54) | GLO1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL3034226 | 0.80 | GLO1 (0.54) | GLO1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL7877613 | 0.79 | GLO1 (0.57) | GLO1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL11097676 | 0.78 | GLO1 (0.77) | GLO1MAPTKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489836-B1 | LIGHT ACTIVATED ACYL-ENZYMES | UNIV DUKE (US) | 1994-12-21 | — | — | EP | disclosed |
| US-5218137-A | Chemical light amplifiers | DUKE UNIVERSITY (US) | 1993-06-08 | — | — | US | disclosed |
| EP-0489836-A4 | LIGHT ACTIVATED ACYL-ENZYMES | — | 1993-05-26 | — | — | EP | disclosed |
| EP-0489836-A1 | LIGHT ACTIVATED ACYL-ENZYMES. | UNIV DUKE (US) | 1992-06-17 | — | — | EP | disclosed |
| US-5114851-A | Serine- or cysteine-containing protease modified by nucleophilic cinnamic acid; photoisomerization; biological switches; medical diagnosis | DUKE UNIVERSITY (US) | 1992-05-19 | — | — | US | disclosed |
| WO-1991003549-A1 | LIGHT ACTIVATED ACYL-ENZYMES | DUKE UNIVERSITY (US) | 1991-03-21 | — | — | WO | disclosed |