SCHEMBL9363151

SCHEMBL9363151

CC(Oc1ccc(Oc2ccc(Cl)cc2)cc1)C(=O)Oc1ccc(Oc2ccc(Cl)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
MEN1 O00255 1/20 0.48
MAPT P10636 1/20 0.48
KMT2A Q03164 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
POLB P06746 1/20 0.47
EPHX2 P34913 1/20 0.45
PPARG P37231 3/20 0.44
PPARA Q07869 3/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23356457 0.95 CYP1A2 (0.54) CYP1A2CYP2C9CYP2C19MEN1MAPT
SCHEMBL11646451 0.94 PPARA (0.53) CYP1A2CYP2C9CYP2C19MAPTPPARG
SCHEMBL9367506 0.89 GAA (0.49) CYP1A2CYP2C9CYP2C19MEN1MAPT
SCHEMBL10175713 0.89 PPARG (0.50) CYP1A2CYP2C9CYP2C19MEN1MAPT
SCHEMBL9362309 0.88 HTR2A (0.50) CYP1A2CYP2C9CYP2C19MEN1MAPT
SCHEMBL20045401 0.87 TDP1 (0.55) CYP1A2CYP2C9CYP2C19MAPTPOLB
SCHEMBL9320809 0.87 MEN1 (0.62) CYP1A2CYP2C9CYP2C19MEN1MAPT
SCHEMBL21991248 0.85 CYP1A2 (0.49) CYP1A2CYP2C9CYP2C19MEN1MAPT
SCHEMBL10964710 0.84 EPHX2 (0.62) CYP1A2CYP2C9CYP2C19MEN1MAPT
SCHEMBL3217144 0.83 CYP1A2 (0.59) CYP1A2CYP2C9CYP2C19POLBEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0303415-B1 Herbicidally active phenoxy-alkanecarboxylic acid derivatives SUNTORY LTD (JP) 1994-11-30 EP disclosed
US-5205855-A Postemergence, preemergence herbicides SUNTORY LIMITED (JP) 1993-04-27 US disclosed
US-4976773-A SELECTIVITY BETWEEN MONOCOYLEDON PLANTS SUNTORY LIMITED (JP) 1990-12-11 US disclosed
EP-0303415-A2 Herbicidally active phenoxy-alkanecarboxylic acid derivatives SUNTORY LIMITED (JP) 1989-02-15 EP disclosed