Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9285601 | 0.95 | MEN1 (0.58) | MEN1KMT2AMAPTL3MBTL1CYP1A2 | |
| SCHEMBL18331472 | 0.95 | MEN1 (0.58) | MEN1KMT2AMAPTL3MBTL1CYP1A2 | |
| SCHEMBL11061091 | 0.89 | MEN1 (0.58) | MEN1KMT2AMAPTL3MBTL1CYP1A2 | |
| SCHEMBL21991482 | 0.87 | HPGD (0.60) | MEN1KMT2AMAPTL3MBTL1CYP1A2 | |
| SCHEMBL11158124 | 0.87 | KMT2A (0.52) | MEN1KMT2AMAPTL3MBTL1CYP1A2 | |
| SCHEMBL9363151 | 0.87 | CYP1A2 (0.50) | MEN1KMT2AMAPTL3MBTL1CYP1A2 | |
| SCHEMBL11319078 | 0.86 | EPHX2 (0.54) | MEN1KMT2AMAPTL3MBTL1CYP1A2 | |
| SCHEMBL4250581 | 0.86 | KMT2A (0.58) | MEN1KMT2AMAPTL3MBTL1CYP1A2 | |
| SCHEMBL21991248 | 0.85 | CYP1A2 (0.49) | MEN1KMT2AMAPTL3MBTL1CYP1A2 | |
| SCHEMBL11168520 | 0.84 | CYP1A2 (0.52) | MEN1KMT2AMAPTL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220409566-A1 | CCL5 Inhibitors | LAPKO INC, dba AFECTA PHARMACEUTICALS | 2022-12-29 | — | — | US | disclosed |
| US-20220142961-A1 | CCL5 Inhibitors | LAPKO INC, dba AFECTA PHARMACEUTICALS | 2022-05-12 | — | — | US | disclosed |
| US-10940132-B2 | CCL5 inhibitors | AFECTA PHARMACEUTICALS, INC. (US) | 2021-03-09 | — | — | US | disclosed |
| US-20200138766-A1 | CCL5 INHIBITORS | LAPKO INC. DBA AFECTA PHARMACEUTICALS | 2020-05-07 | — | — | US | disclosed |
| US-5308830-A | Low dosage; nonphytotoxic to crops; pre- and postemergence | ROHM AND HAAS COMPANY (US) | 1994-05-03 | — | — | US | disclosed |
| US-5304531-A | Preemergent, postemergent, controls weed growth 2-chloro-4-trifluoromethyl-3' (1-(carboethoxy) ethoxycarbonyl)-4-nitrodiphenyl ether | BASF CORPORATION | 1994-04-19 | — | — | US | disclosed |
| US-4894479-A | CARBONYLOXYAMINO DERIVATIVES | ROHM AND HAAS COMPANY (US) | 1990-01-16 | — | — | US | disclosed |
| US-4863507-A | Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0047972-B1 | ENHANCEMENT OF CARBOHYDRATE DEPOSITION IN PLANTS WITH SUBSTITUTED PHENOXYALKANOIC-ACID AND CYCLOHEXANE-DIONE DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-10-30 | — | — | EP | disclosed |
| US-4531969-A | Combatting growth of weeds | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-07-30 | — | — | US | disclosed |
| US-4386954-A | Herbicidal diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1983-06-07 | — | — | US | disclosed |
| US-4252980-A | Process for the manufacture of (phenoxy or benzyl)-phenoxypropionic acid methyl esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | disclosed |
| EP-0020052-A1 | Novel substituted nitrodiphenyl ethers, herbicidal compositions containing them, processes for the preparation thereof and the use thereof for combating weeds | ROHM AND HAAS COMPANY (US) | 1980-12-10 | — | — | EP | disclosed |
| US-4047929-A | 3-METHYL-4-AMINO-6-PHENYL-1,2,4-TRIAZIN-5-ONE, 4-PHENOXY-PHENOXY-ALKANECARBOXYLIC ACID | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |
| US-3985875-A | RENIN INHIBITION, ANTIHYPERTENSIVE, ANTICHOLESTEROL AGENTS | DAINIPPON PHARMACEUTICAL CO., LTD. (JA) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220142961-A1 | CCL5 Inhibitors | CCL5, CCL11, CCR5 | MEN1 3749/4885KMT2A 4842/4885MAPT 4264/4885 |
| US-20200138766-A1 | CCL5 INHIBITORS | CCL5, CCL11, CCR5 | MEN1 3749/4885KMT2A 4842/4885MAPT 4264/4885 |
| US-10940132-B2 | CCL5 inhibitors | CCL5, CCL11, CCR5 | MEN1 3749/4885KMT2A 4842/4885MAPT 4264/4885 |
| US-20220409566-A1 | CCL5 Inhibitors | CCL5, CCL11, CCR5 | MEN1 3749/4885KMT2A 4842/4885MAPT 4264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.