SCHEMBL20045401

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23356457	0.92	CYP1A2 (0.54)	TDP1CYP1A2CYP2C9CYP2C19POLB
	SCHEMBL9363151	0.87	CYP1A2 (0.50)	PPARGPPARACYP1A2CYP2C9CYP2C19
	SCHEMBL10175713	0.86	PPARG (0.50)	TDP1ALDH1A1PPARGPPARACYP1A2
	SCHEMBL11646451	0.82	PPARA (0.53)	TDP1PPARGPPARACYP1A2CYP2C9
	SCHEMBL11609867	0.80	CYP1A2 (0.55)	ALDH1A1PPARGPPARACYP1A2CYP2C9
	SCHEMBL18331157	0.80	HTR2A (0.53)	TDP1ALDH1A1CYP1A2CYP2C9CYP2C19
	SCHEMBL23368102	0.80	HTR2A (0.53)	TDP1ALDH1A1CYP1A2CYP2C9CYP2C19
	SCHEMBL9285601	0.78	MEN1 (0.58)	ALDH1A1CYP1A2CYP2C9CYP2C19POLB
	SCHEMBL18331472	0.78	MEN1 (0.58)	ALDH1A1CYP1A2CYP2C9CYP2C19POLB
	SCHEMBL5108544	0.78	ALDH1A1 (0.65)	TDP1ALDH1A1POLBSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.