Dinaline

Dinaline

SCHEMBL93636

Nc1ccc(C(=O)Nc2ccccc2N)cc1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 18/20 0.79
HDAC3 O15379 10/20 0.79
HDAC2 Q92769 10/20 0.79
MAPK1 P28482 1/20 0.79
NCOR2 Q9Y618 4/20 0.75
PTGS1 P23219 1/20 0.71
HDAC4 P56524 3/20 0.69
HDAC7 Q8WUI4 3/20 0.69
HDAC10 Q969S8 3/20 0.69
HDAC11 Q96DB2 3/20 0.69
HDAC8 Q9BY41 3/20 0.69
HDAC6 Q9UBN7 3/20 0.69
HDAC9 Q9UKV0 3/20 0.69
HDAC5 Q9UQL6 3/20 0.69
NPC1 O15118 1/20 0.60
RAB9A P51151 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dinaline SCHEMBL29354254 1.00 HDAC1 (0.79) HDAC1HDAC3HDAC2MAPK1NCOR2
Dinaline SCHEMBL10373837 0.98 HDAC1 (0.77) HDAC1HDAC3HDAC2MAPK1NCOR2
SCHEMBL8401704 0.94 HDAC1 (0.89) HDAC1HDAC3HDAC2MAPK1NCOR2
Dinaline SCHEMBL27308145 0.93 HDAC1 (0.70) HDAC1HDAC3HDAC2MAPK1NCOR2
Dinaline SCHEMBL21797218 0.91 HDAC1 (0.76) HDAC1HDAC3HDAC2MAPK1NCOR2
SCHEMBL17744864 0.90 MEN1 (0.66) HDAC1HDAC3HDAC2MAPK1NCOR2
SCHEMBL1060598 0.89 HDAC1 (0.79) HDAC1HDAC3HDAC2MAPK1NCOR2
SCHEMBL30363156 0.89 HDAC1 (1.00) HDAC1HDAC3HDAC2MAPK1NCOR2
SCHEMBL407834 0.89 HDAC1 (1.00) HDAC1HDAC3HDAC2MAPK1NCOR2
SCHEMBL23500754 0.87 HDAC1 (0.83) HDAC1HDAC3HDAC2MAPK1NCOR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118853067-B Polyamide-imide adhesive and camera element protective film adhesive tape prepared from same 东莞市乔竣电子科技有限公司 2025-05-30 CN claimed
CN-116199587-B Synthesis method of dinaline hydrochloride 厦门欧瑞捷生物科技有限公司 2024-12-17 CN claimed
CN-118853067-A Polyamide-imide adhesive and camera element protective film adhesive tape prepared from same 东莞市乔竣电子科技有限公司 2024-10-29 CN claimed
CN-113979873-B Preparation method of dinaline hydrochloride 齐鲁动物保健品有限公司 2024-02-13 CN claimed
CN-114181710-B Saline-alkali soil curing agent and preparation method thereof 中国科学院烟台海岸带研究所 2024-01-09 CN claimed
CN-116549385-A Preparation method of dinaline hydrochloride injection 天津市中升挑战生物科技有限公司 2023-08-08 CN claimed
CN-116199587-A Synthesis method of dinaline hydrochloride 厦门欧瑞捷生物科技有限公司 2023-06-02 CN claimed
EP-2459227-B1 Prodrugs containing an aromatic amine connected by an amide bond to a carrier ASCENDIS PHARMA AS (DK) 2021-03-17 EP claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
CN-104244968-A PH20 polypeptide variants, formulations, and uses thereof HALOZYME INC 2014-12-24 CN claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
EP-1919929-A4 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS RND PHARMACEUTICALS INC (US) 2008-08-06 EP claimed
EP-1919929-A2 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS RND Pharmaceuticals, Inc. (US) 2008-05-14 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
WO-2007019221-A2 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS RND PHARMACEUTICALS, INC. (US) 2007-02-15 WO claimed
EP-0393575-B1 Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent SEARLE & CO (US) 1994-03-16 EP claimed
EP-0393575-A1 Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent G.D. Searle & Co. (US) 1990-10-24 EP claimed
US-4933368-A FOR ADMINISTERING TO REAT REFRACTORY TUMORS IN MAMMALS GODECKE AKTIENGESELLSCHAFT (DE) 1990-06-12 US claimed