Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 5/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363641 | 0.80 | HPGD (0.68) | LSSCYP1A2CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL9523780 | 0.80 | LSS (0.55) | LSSCYP1A2CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL9523895 | 0.80 | CYP2C19 (0.60) | LSSCYP1A2CYP2D6CYP2C19CYP2C9 | |
| Hydrochloric Acid SCHEMBL9368954 | 0.79 | HPGD (0.66) | LSSCYP1A2CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL9524466 | 0.77 | LSS (0.53) | LSSCYP1A2CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL8534514 | 0.76 | HTR2A (0.51) | LSSCYP1A2CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL8540469 | 0.76 | LSS (0.81) | LSSCYP2D6CYP2C19KMT2ACYP3A4 | |
| SCHEMBL8535599 | 0.75 | LSS (0.50) | LSSCYP1A2CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL8534116 | 0.74 | LSS (0.49) | LSSCYP2D6CYP2C19DRD3KMT2A | |
| SCHEMBL8537652 | 0.74 | CYP1A2 (0.47) | LSSCYP1A2CYP2D6CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4804662-A | Substituted 4-(1H-imidazol-1-yl)benzamides as antiarrhythmic agents | SCHERING A.G. (DE) | 1989-02-14 | — | — | US | disclosed |