⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3578716 | 0.71 | — | — | |
| SCHEMBL191728 | 0.71 | — | — | |
| SCHEMBL9573401 | 0.71 | — | — | |
| SCHEMBL5785619 | 0.69 | — | — | |
| SCHEMBL2762826 | 0.69 | — | — | |
| SCHEMBL16316843 | 0.69 | — | — | |
| SCHEMBL3266002 | 0.69 | — | — | |
| SCHEMBL22203314 | 0.69 | — | — | |
| SCHEMBL28349894 | 0.65 | TGFBR1 (0.33) | — | |
| SCHEMBL16051165 | 0.65 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555351-B1 | OXYSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 1994-12-28 | — | — | EP | disclosed |
| US-5245068-A | Acylcoenzyme A cholesterol acyltransferase inhibitors | WARNER-LAMBERT COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0555351-A1 | OXYSULFONYL CARBAMATES. | WARNER LAMBERT CO (US) | 1993-08-18 | — | — | EP | disclosed |
| WO-1992007826-A1 | OXYSULFONYL CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |