Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCE | Q02156 | 3/20 | 0.36 |
| ▸ | MYLK | Q15746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684250 | 0.90 | PRKCE (0.38) | PRKCEMYLKTDP1MAPTMEN1 | |
| SCHEMBL2649083 | 0.85 | GABRA1 (0.44) | GABRA1GABRG2GABRB3HSP90AA1HSP90AB1 | |
| SCHEMBL28769248 | 0.75 | POLB (0.40) | PRKCEMYLKTDP1MAPTMEN1 | |
| SCHEMBL9861626 | 0.74 | HSP90AA1 (0.43) | GABRA1GABRG2GABRB3HSP90AA1HSP90AB1 | |
| SCHEMBL26137552 | 0.73 | PRKCE (0.36) | PRKCEMYLKTDP1MAPTMEN1 | |
| SCHEMBL27505166 | 0.73 | GABRA1 (0.35) | GABRA1GABRG2GABRB3HSP90AA1HSP90AB1 | |
| SCHEMBL9363999 | 0.73 | ERN1 (0.33) | PRKCEMYLKTDP1MAPTMEN1 | |
| SCHEMBL22380325 | 0.71 | GABRA1 (0.40) | MAPTGABRA1GABRG2GABRB3HSP90AA1 | |
| SCHEMBL30631021 | 0.70 | PRKCE (0.39) | PRKCEMYLKTDP1MAPTMEN1 | |
| SCHEMBL12807838 | 0.70 | CYP1A2 (0.31) | PRKCEMYLKTDP1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388732-B1 | Pentasubstituted phenyls | BAYER AG (DE) | 1994-04-27 | — | — | EP | disclosed |
| US-5138090-A | Administering to inhibit HMG-CoA reductase | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |
| EP-0388732-A2 | Pentasubstituted phenyls | BAYER AG (DE) | 1990-09-26 | — | — | EP | disclosed |