SCHEMBL9684250

SCHEMBL9684250

COCc1cc(COC)c(C(C)C)cc1C(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCE Q02156 3/20 0.38
ALDH1A1 P00352 3/20 0.38
MYLK Q15746 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
MEN1 O00255 1/20 0.38
PRKCG P05129 1/20 0.38
MAPT P10636 1/20 0.38
PRKCA P17252 1/20 0.38
APEX1 P27695 1/20 0.38
RECQL P46063 1/20 0.38
KMT2A Q03164 1/20 0.38
P2RX3 P56373 1/20 0.32
P2RX2 Q9UBL9 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
POLB P06746 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GAA P10253 2/20 0.31
GFER P55789 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9364012 0.90 PRKCE (0.36) PRKCEALDH1A1MYLKTDP1MEN1
SCHEMBL26137552 0.81 PRKCE (0.36) PRKCEALDH1A1MYLKTDP1MEN1
SCHEMBL9363999 0.81 ERN1 (0.33) PRKCEALDH1A1MYLKTDP1MEN1
SCHEMBL28769248 0.80 POLB (0.40) PRKCEALDH1A1MYLKTDP1MEN1
SCHEMBL12807838 0.78 CYP1A2 (0.31) PRKCEALDH1A1MYLKTDP1MEN1
SCHEMBL8750562 0.77 IDO1 (0.37) PRKCEALDH1A1MYLKTDP1MEN1
SCHEMBL26137545 0.77 IDO1 (0.37) PRKCEALDH1A1MYLKTDP1MEN1
SCHEMBL26137718 0.77 TRPA1 (0.47) ALDH1A1TDP1LMNAKDM4E
SCHEMBL25625702 0.77 KDM4E (0.42) ALDH1A1TDP1LMNAKDM4E
SCHEMBL3356030 0.76 ALDH1A1 (0.48) PRKCEALDH1A1MYLKTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5122442-A Water soluble binder; photosensitive compound HOECHST CELANESE CORPORATION (US) 1992-06-16 US disclosed
EP-0212482-B1 PROCESS FOR OBTAINING NEGATIVE IMAGES FROM POSITIVE PHOTORESISTS HOECHST CELANESE CORPORATION (US) 1989-04-19 EP disclosed
EP-0212482-A2 Process for obtaining negative images from positive photoresists HOECHST CELANESE CORPORATION (US) 1987-03-04 EP disclosed
US-4436804-A Light-sensitive polymeric diazonium condensates and reproduction compositions and materials therewith AMERICAN HOECHST CORPORATION (US) 1984-03-13 US disclosed