Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018763 | 1.00 | L3MBTL1 (0.41) | L3MBTL1SLC1A2SLC1A1PKMDPP4 | |
| SCHEMBL9664087 | 0.81 | L3MBTL1 (0.45) | L3MBTL1 | |
| SCHEMBL10753923 | 0.75 | — | — | |
| SCHEMBL2460430 | 0.74 | CHRM2 (0.35) | — | |
| SCHEMBL10818536 | 0.74 | CHRM2 (0.35) | — | |
| SCHEMBL6578062 | 0.74 | CHRM2 (0.35) | — | |
| SCHEMBL10588318 | 0.74 | CHRM2 (0.35) | — | |
| SCHEMBL5183989 | 0.74 | CHRM2 (0.35) | — | |
| SCHEMBL10817753 | 0.74 | CHRM2 (0.35) | — | |
| SCHEMBL9326179 | 0.74 | CHRM2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413277-B1 | Peptide antagonists of bradykinin | HOECHST AG (DE) | 1994-11-23 | — | — | EP | claimed |
| EP-0564972-A2 | Peptides with N-terminal modifications having bradykinin antagonistic activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-13 | — | — | EP | claimed |
| EP-0455133-A2 | Peptide antagonists of bradykinin | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-06 | — | — | EP | claimed |
| EP-0413277-A1 | Peptide antagonists of bradykinin | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-20 | — | — | EP | claimed |
| EP-0413277-B1 | Peptide antagonists of bradykinin | HOECHST AG (DE) | 1994-11-23 | — | — | EP | disclosed |
| EP-0564972-A2 | Peptides with N-terminal modifications having bradykinin antagonistic activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-13 | — | — | EP | disclosed |
| EP-0455133-A2 | Peptide antagonists of bradykinin | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-06 | — | — | EP | disclosed |
| EP-0413277-A1 | Peptide antagonists of bradykinin | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-20 | — | — | EP | disclosed |