Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 4/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364137 | 0.93 | APEX1 (0.40) | APEX1GRIK1GRIK2ALDH1A1TSHR | |
| SCHEMBL9364132 | 0.93 | APEX1 (0.40) | APEX1GRIK1GRIK2ALDH1A1TSHR | |
| SCHEMBL4278693 | 0.82 | GRIK1 (0.43) | APEX1GRIK1GRIK2ALDH1A1TSHR | |
| SCHEMBL28066899 | 0.80 | EP300 (0.51) | APEX1GRIK1 | |
| SCHEMBL4278699 | 0.78 | GRIK1 (0.41) | GRIK1GRIK2ALDH1A1TSHRTHRB | |
| SCHEMBL28066860 | 0.75 | EP300 (0.53) | APEX1GRIK1 | |
| SCHEMBL9446544 | 0.75 | EP300 (0.53) | APEX1GRIK1 | |
| SCHEMBL28950882 | 0.74 | CPB1 (0.49) | APEX1GRIK1GRIK2ALDH1A1TSHR | |
| SCHEMBL10386720 | 0.74 | TSHR (0.43) | APEX1ALDH1A1TSHRTHRB | |
| SCHEMBL9008292 | 0.74 | TSHR (0.43) | APEX1ALDH1A1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455585-B1 | Unsaturated urea polysiloxanes | CIBA GEIGY AG (CH) | 1994-03-23 | — | — | EP | claimed |
| EP-0455585-A1 | Unsaturated urea polysiloxanes | CIBA-GEIGY AG (CH) | 1991-11-06 | — | — | EP | claimed |
| EP-0455585-B1 | Unsaturated urea polysiloxanes | CIBA GEIGY AG (CH) | 1994-03-23 | — | — | EP | disclosed |
| EP-0455585-A1 | Unsaturated urea polysiloxanes | CIBA-GEIGY AG (CH) | 1991-11-06 | — | — | EP | disclosed |