SCHEMBL4278693

SCHEMBL4278693

CC/C=C(/CCOCC)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.43
GRIK2 Q13002 2/20 0.43
ALDH1A1 P00352 2/20 0.38
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.33
APEX1 P27695 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30355289 0.84 TSHR (0.50) GRIK1GRIK2ALDH1A1TSHRTHRB
SCHEMBL31196850 0.84 THRB (0.38) GRIK1GRIK2ALDH1A1TSHRTHRB
SCHEMBL9364144 0.82 APEX1 (0.37) GRIK1GRIK2ALDH1A1TSHRTHRB
SCHEMBL9008292 0.80 TSHR (0.43) ALDH1A1TSHRTHRBAPEX1
SCHEMBL10386720 0.80 TSHR (0.43) ALDH1A1TSHRTHRBAPEX1
SCHEMBL28066899 0.79 EP300 (0.51) GRIK1APEX1
SCHEMBL1415424 0.78 ALDH1A1 (0.36) ALDH1A1TSHRTHRBAPEX1
SCHEMBL9364137 0.78 APEX1 (0.40) GRIK1GRIK2ALDH1A1TSHRTHRB
SCHEMBL9364132 0.78 APEX1 (0.40) GRIK1GRIK2ALDH1A1TSHRTHRB
SCHEMBL20495665 0.77 ALDH1A1 (0.35) ALDH1A1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090068342-A1 POSITIVE PHOTORESIST COMPOSITION, THICK FILM PHOTORESIST LAMINATE, METHOD FOR PRODUCING THICK FILM RESIST PATTERN, AND METHOD FOR PRODUCING CONNECTING TERMINAL TOKYO OHKA KOGYO CO., LTD. (JP) 2009-03-12 US disclosed