Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582553 | 1.00 | CYP3A4 (0.61) | CYP3A4HSD17B10TDP1TAAR1ALDH1A1 | |
| SCHEMBL9325209 | 1.00 | CYP3A4 (0.61) | CYP3A4HSD17B10TDP1TAAR1ALDH1A1 | |
| SCHEMBL9364149 | 1.00 | CYP3A4 (0.61) | CYP3A4HSD17B10TDP1TAAR1ALDH1A1 | |
| SCHEMBL9359942 | 0.91 | CYP3A4 (0.54) | CYP3A4HSD17B10TDP1TAAR1ALDH1A1 | |
| SCHEMBL26567850 | 0.90 | CYP3A4 (0.50) | CYP3A4HSD17B10TDP1TAAR1ALDH1A1 | |
| SCHEMBL1224397 | 0.88 | MAPT (0.56) | CYP3A4HSD17B10TDP1TAAR1ALDH1A1 | |
| SCHEMBL17122821 | 0.83 | L3MBTL1 (0.66) | CYP3A4HSD17B10TDP1TAAR1ALDH1A1 | |
| SCHEMBL13310879 | 0.83 | CYP3A4 (0.78) | CYP3A4HSD17B10TDP1TAAR1ALDH1A1 | |
| SCHEMBL807664 | 0.83 | CYP3A4 (0.78) | CYP3A4HSD17B10TDP1TAAR1ALDH1A1 | |
| SCHEMBL20323054 | 0.83 | CYP3A4 (0.78) | CYP3A4HSD17B10TDP1TAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317233-B1 | Tetraphenylthiophene derivative and electrophotographic photoreceptor containing same | MITSUI TOATSU CHEMICALS (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5023343-A | Charge transfer compound | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-06-11 | — | — | US | disclosed |
| US-4963449-A | P-amino substituted tetraphenylthiophenes and electrophotographic photoreceptors containing them | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0317233-A2 | Tetraphenylthiophene derivative and electrophotographic photoreceptor containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-05-24 | — | — | EP | disclosed |