SCHEMBL1224397

SCHEMBL1224397

c1ccc(-c2sc(-c3ccccc3)c(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.56
CYP1A2 P05177 3/20 0.56
CYP2D6 P10635 3/20 0.56
CYP2C19 P33261 3/20 0.56
CYP3A4 P08684 3/20 0.56
KDM4E B2RXH2 2/20 0.56
CYP2C9 P11712 2/20 0.56
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
ALDH1A1 P00352 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.42
PTGS2 P35354 2/20 0.41
GAA P10253 1/20 0.41
ALOX5 P09917 1/20 0.40
GRM6 O15303 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CHEK1 O14757 1/20 0.38
AKT2 P31751 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL8752125 0.90 MAPT (0.48) MAPTCYP1A2CYP2D6CYP2C19CYP3A4
SCHEMBL28123162 0.90 MAPT (0.48) MAPTCYP1A2CYP2D6CYP2C19CYP3A4
SCHEMBL8582553 0.88 CYP3A4 (0.61) MAPTCYP1A2CYP2D6CYP2C19CYP3A4
SCHEMBL9364153 0.88 CYP3A4 (0.61) MAPTCYP1A2CYP2D6CYP2C19CYP3A4
SCHEMBL9364149 0.88 CYP3A4 (0.61) MAPTCYP1A2CYP2D6CYP2C19CYP3A4
SCHEMBL12854147 0.88 MAPT (0.46) MAPTCYP1A2CYP2D6CYP2C19CYP3A4
SCHEMBL9325209 0.88 CYP3A4 (0.61) MAPTCYP1A2CYP2D6CYP2C19CYP3A4
SCHEMBL24817276 0.86 ALDH1A1 (0.58) MAPTCYP1A2CYP2D6CYP2C19CYP3A4
SCHEMBL16376531 0.86 KDM4E (0.83) MAPTCYP1A2CYP2D6CYP2C19CYP3A4
SCHEMBL12262883 0.86 ALOX5 (0.51) MAPTCYP1A2CYP2D6CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118117166-A Detection method for detecting electrolyte state, electrolyte system, battery, vehicle and application 北京车和家汽车科技有限公司 2024-05-31 CN claimed
CN-114805756-B Adamantyl microporous material and preparation method thereof 北方民族大学 2023-07-07 CN claimed
CN-114805756-A Adamantyl microporous material and preparation method thereof 北方民族大学 2022-07-29 CN claimed
CN-113621363-A Fluorescent thermosetting resin microsphere and preparation and application thereof 苏州妥璞智能科技有限公司 2021-11-09 CN claimed
US-11149209-B2 Process for oxidation of organosulfur compounds UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2021-10-19 US claimed
CN-109305955-B Preparation method of molecular glass photoresist containing tetraphenylthiophenol structure 深圳前海广宇天骥科技有限公司 2020-12-22 CN claimed
CN-110564093-B Adjustable fluorescent ion gel with multiple stimulus responsiveness 北京大学 2020-07-28 CN claimed
US-20200216762-A1 PROCESS FOR OXIDATION OF ORGANOSULFUR COMPOUNDS NANOGAP SUB NM POWDER, S.A. (ES) 2020-07-09 US claimed
CN-110518450-B Preparation method of light-induced condensing laser and light-induced condensing laser 华南理工大学 2020-04-24 CN claimed
CN-110564093-A Adjustable fluorescent ion gel with multiple stimulus responsiveness 北京大学 2019-12-13 CN claimed
CN-106461641-A Light-up probes based on fluorogens with aggregation induced emission characteristics for cellular imaging and drug screening 新加坡国立大学 2017-02-22 CN claimed
CN-102881451-A All-solid-state power storage device CHINESE ACAD INST CHEMISTRY 2013-01-16 CN claimed
US-20070116981-A1 Single-layer organic el device ISOBE, SHINICHIRO (JP) 2007-05-24 US claimed
EP-1715019-A1 SINGLE-LAYER ORGANIC EL DEVICE Mitsubishi Heavy Industries, Ltd. (JP) 2006-10-25 EP claimed
EP-0727713-A1 Photoresist having increased sensitivity and use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1996-08-21 EP claimed
WO-1995020637-A2 HYDROCARBON OIL-AQUEOUS FUEL AND ADDITIVE COMPOSITIONS MEG S.N.C. DI SCOPELLITI SOFIA & C. (IT) 1995-08-03 WO claimed
EP-0317233-B1 Tetraphenylthiophene derivative and electrophotographic photoreceptor containing same MITSUI TOATSU CHEMICALS (JP) 1994-05-04 EP claimed
US-5023343-A Charge transfer compound MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1991-06-11 US claimed
US-4963449-A P-amino substituted tetraphenylthiophenes and electrophotographic photoreceptors containing them MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1990-10-16 US claimed
EP-0317233-A2 Tetraphenylthiophene derivative and electrophotographic photoreceptor containing same MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-05-24 EP claimed