Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10810480 | 0.81 | CYP19A1 (0.57) | CYP19A1HSP90AA1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10508172 | 0.78 | EGLN3 (0.45) | CYP19A1HSP90AA1MAPT | |
| SCHEMBL11246598 | 0.77 | CYP19A1 (0.59) | CYP19A1HSP90AA1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2917482 | 0.73 | CYP19A1 (1.00) | CYP19A1HSP90AA1LMNANPC1RAB9A | |
| SCHEMBL23219686 | 0.73 | EGLN3 (0.42) | CYP19A1HSP90AA1MEN1KMT2AMAPT | |
| SCHEMBL10247229 | 0.72 | HMOX1 (0.61) | CYP19A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL9382670 | 0.72 | CYP19A1 (0.96) | CYP19A1HSP90AA1LMNANPC1RAB9A | |
| SCHEMBL9023539 | 0.71 | CYP19A1 (0.86) | CYP19A1HSP90AA1LMNANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL411908 | 0.71 | HMOX1 (0.59) | CYP19A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7138301 | 0.70 | CYP19A1 (0.67) | CYP19A1HSP90AA1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455052-B1 | 5-(1,2,4-Triazol-l-ylmethyl)-isoxazoline | BASF AG (DE) | 1994-07-27 | — | — | EP | disclosed |
| US-5156669-A | Fungicides and plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1992-10-20 | — | — | US | disclosed |
| EP-0455052-A1 | 5-(1,2,4-Triazol-l-ylmethyl)-isoxazoline | BASF Aktiengesellschaft (DE) | 1991-11-06 | — | — | EP | disclosed |