Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL801703 | 0.81 | NOTUM (0.63) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL6892003 | 0.78 | NOTUM (0.59) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL8047855 | 0.78 | LMNA (0.55) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL8278915 | 0.78 | LMNA (0.59) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL6895118 | 0.78 | ENPP2 (0.59) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL4876009 | 0.78 | LMNA (0.44) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL2532397 | 0.76 | LMNA (0.78) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL10311213 | 0.75 | CYP3A4 (0.53) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL14438346 | 0.74 | TDP1 (0.56) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL27513743 | 0.74 | CYP3A4 (0.59) | LMNAMAPTENPP2MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445698-B1 | Thiocarbamoylacetonitrile compounds | MITSUBISHI CHEM IND (JP) | 1994-06-22 | — | — | EP | disclosed |
| US-5246958-A | Thiocarbamoylacetonitriles | MITSUBISHI KASEI CORPORATION (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0445698-A1 | Thiocarbamoylacetonitrile compounds | MITSUBISHI KASEI CORPORATION (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-4226878-A | ANTIINFLAMMATORY, HYPOTENSIVES, ANTIHISTAMINES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1980-10-07 | — | — | US | disclosed |