Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364399 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRLMNACYP3A4HSD17B10 | |
| SCHEMBL9360085 | 0.85 | GAA (0.48) | ALDH1A1TSHRLMNACYP3A4HSD17B10 | |
| SCHEMBL9360083 | 0.85 | GAA (0.48) | ALDH1A1TSHRLMNACYP3A4HSD17B10 | |
| SCHEMBL9359888 | 0.83 | LMNA (0.49) | ALDH1A1TSHRLMNACYP3A4HSD17B10 | |
| SCHEMBL9359884 | 0.83 | LMNA (0.49) | ALDH1A1TSHRLMNACYP3A4HSD17B10 | |
| SCHEMBL9360657 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TSHRLMNACYP3A4HSD17B10 | |
| SCHEMBL9360086 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TSHRLMNACYP3A4TP53 | |
| SCHEMBL9360090 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TSHRLMNACYP3A4TP53 | |
| SCHEMBL27585866 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TSHRLMNACYP3A4HSD17B10 | |
| Water SCHEMBL27487586 | 0.77 | TSHR (0.59) | ALDH1A1TSHRLMNACYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393713-B1 | Process for the preparation of N-substituted maleimides | TOSOH CORP (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5087705-A | Heating N-substituted maleamic acid monoester in presence of acid catalyst | SHIN-DAIKYOWA PETROCHEMICAL CO., LTD. (JP) | 1992-02-11 | — | — | US | disclosed |