Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364421 | 1.00 | ALDH1A1 (0.46) | ALDH1A1ESR1MAPTNPC1RAB9A | |
| SCHEMBL9363923 | 0.85 | TSHR (0.47) | ALDH1A1MAPTL3MBTL1TSHRPKM | |
| SCHEMBL9363917 | 0.85 | TSHR (0.47) | ALDH1A1MAPTL3MBTL1TSHRPKM | |
| SCHEMBL9360090 | 0.84 | ALDH1A1 (0.48) | ALDH1A1ESR1MAPTNPC1RAB9A | |
| SCHEMBL9360086 | 0.84 | ALDH1A1 (0.48) | ALDH1A1ESR1MAPTNPC1RAB9A | |
| SCHEMBL9359700 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTNPC1RAB9ATSHR | |
| SCHEMBL9359707 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTNPC1RAB9ATSHR | |
| SCHEMBL9359884 | 0.83 | LMNA (0.49) | ALDH1A1MAPTNPC1RAB9ATSHR | |
| SCHEMBL9359888 | 0.83 | LMNA (0.49) | ALDH1A1MAPTNPC1RAB9ATSHR | |
| SCHEMBL20597787 | 0.79 | ALDH1A1 (0.50) | ALDH1A1ESR1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393713-B1 | Process for the preparation of N-substituted maleimides | TOSOH CORP (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5087705-A | Heating N-substituted maleamic acid monoester in presence of acid catalyst | SHIN-DAIKYOWA PETROCHEMICAL CO., LTD. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0393713-A1 | Process for the preparation of N-substituted maleimides | Tosoh Corporation (JP) | 1990-10-24 | — | — | EP | disclosed |