Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360657 | 0.85 | ALDH1A1 (0.46) | LMNAALDH1A1SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL9360083 | 0.80 | GAA (0.48) | LMNAALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL9360085 | 0.80 | GAA (0.48) | LMNAALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL9363967 | 0.78 | TSHR (0.55) | LMNAALDH1A1SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL9363974 | 0.78 | TSHR (0.55) | LMNAALDH1A1SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL7548898 | 0.78 | TSHR (0.50) | GPR35LMNAALDH1A1SMN1; SMN2TAS1R3 | |
| SCHEMBL11418791 | 0.75 | TSHR (0.63) | LMNAALDH1A1SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL9512856 | 0.75 | TSHR (0.53) | LMNAALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9512853 | 0.75 | TSHR (0.53) | LMNAALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9363953 | 0.74 | SMN1; SMN2 (0.47) | LMNAALDH1A1SMN1; SMN2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393713-B1 | Process for the preparation of N-substituted maleimides | TOSOH CORP (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5087705-A | Heating N-substituted maleamic acid monoester in presence of acid catalyst | SHIN-DAIKYOWA PETROCHEMICAL CO., LTD. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0393713-A1 | Process for the preparation of N-substituted maleimides | Tosoh Corporation (JP) | 1990-10-24 | — | — | EP | disclosed |