Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523223 | 0.84 | HTT (0.52) | LMNARAB9AMEN1POLBKMT2A | |
| SCHEMBL2449415 | 0.84 | KDM4E (0.52) | LMNANPC1RAB9ACYP1A2CYP3A4 | |
| Hydroxylated Completely Delakylated Diethylpropion SCHEMBL5319402 | 0.82 | CA1 (0.50) | LMNACYP3A4MAPTPKMHIF1A | |
| Hydroxylated Completely Delakylated Diethylpropion SCHEMBL27460979 | 0.82 | CA1 (0.50) | LMNACYP3A4MAPTPKMHIF1A | |
| SCHEMBL28228323 | 0.82 | ALDH1A1 (0.52) | LMNANPC1RAB9ASLC6A3MEN1 | |
| SCHEMBL31533508 | 0.82 | PARP10 (0.45) | LMNANPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL2631353 | 0.82 | ALDH1A1 (0.52) | LMNANPC1RAB9ASLC6A3MEN1 | |
| SCHEMBL16694617 | 0.82 | ALDH1A1 (0.52) | LMNANPC1RAB9ASLC6A3MEN1 | |
| SCHEMBL3852076 | 0.80 | CES2 (0.50) | NPC1RAB9AMAPTSLC6A3POLB | |
| SCHEMBL9040426 | 0.80 | CES2 (0.50) | LMNARAB9AMAPTSLC6A3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0138714-B1 | 1-(ACETYLAMINOPHENYL)-2-AMINO-PROPANONE DERIVATIVES, THEIR THERAPEUTICAL USE AND PROCESS FOR THEIR PREPARATION | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1987-05-20 | — | — | EP | claimed |
| EP-2215092-B1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INT (DE) | 2012-01-25 | — | — | EP | disclosed |
| EP-0426562-B1 | 1-(4-Aminophenyl)-2-piperidinopropanone derivatives, process for their preparation and their therapeutic use | LAFON LABOR (FR) | 1994-03-16 | — | — | EP | disclosed |
| EP-0325247-B1 | CAMPTOTHECIN DERIVATIVES AND PROCESS FOR PREPARING SAME | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-5128349-A | Vasodilators; cardiovascular disorders | LABORATOIRE L. LAFON (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5061800-A | ANTITUMOR AGENTS | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0426562-A1 | 1-(4-Aminophenyl)-2-piperidinopropanone derivatives, process for their preparation and their therapeutic use | LABORATOIRE L. LAFON (FR) | 1991-05-08 | — | — | EP | disclosed |
| EP-0325247-A1 | Camptothecin derivatives and process for preparing same | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1989-07-26 | — | — | EP | disclosed |