Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL90862 | 0.73 | KDM4E (0.34) | MAPTKDM4E | |
| SCHEMBL11876056 | 0.71 | MEN1 (0.42) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL10752767 | 0.68 | — | — | |
| SCHEMBL9370007 | 0.68 | ALDH1A1 (0.33) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL8016907 | 0.67 | — | — | |
| SCHEMBL7555586 | 0.66 | — | — | |
| SCHEMBL1110848 | 0.66 | MEN1 (0.44) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6627174 | 0.66 | HPGD (0.49) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL59107 | 0.66 | MAPT (0.47) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL64072 | 0.66 | CYP3A4 (0.33) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095925-B2 | Herbicidal imidazole, pyrazole, thiazole and isothiazole derivatives | DU PONT (US) | 1994-12-07 | — | — | EP | disclosed |
| US-4946496-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-08-07 | — | — | US | disclosed |
| US-4931081-A | Herbicidal diazoles sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-06-05 | — | — | US | disclosed |