Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6629853 | 0.78 | HTT (0.50) | HPGDMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL1267770 | 0.76 | HPGD (0.39) | HPGDMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL7064321 | 0.73 | IDH1 (0.39) | HPGDMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL8466325 | 0.73 | HDAC1 (0.34) | KMT2AALDH1A1HTTGAAKDM4E | |
| SCHEMBL6628026 | 0.72 | LMNA (0.52) | HPGDMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL6582698 | 0.72 | RAB9A (0.42) | HPGDMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL6482032 | 0.72 | KDM4E (0.51) | L3MBTL1ALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL6627821 | 0.71 | MEN1 (0.39) | HPGDMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL11876056 | 0.71 | MEN1 (0.42) | HPGDMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL4266835 | 0.71 | ALDH1A1 (0.61) | HPGDMEN1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004525942-A | — | — | 2004-08-26 | — | — | JP | claimed |
| US-20040116495-A1 | Compounds and methods | SMITHKLINE BEECHAM CORPORATION | 2004-06-17 | — | — | US | claimed |
| EP-1379241-A1 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2004-01-14 | — | — | EP | claimed |
| WO-2002078699-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-10 | — | — | WO | claimed |
| US-20040116495-A1 | Compounds and methods | SMITHKLINE BEECHAM CORPORATION | 2004-06-17 | — | — | US | disclosed |
| EP-1379241-A1 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002078699-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-10 | — | — | WO | disclosed |