Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.53 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360287 | 0.97 | NPSR1 (0.70) | KDM4ENPSR1MEN1CYP1A2CYP2C19 | |
| SCHEMBL9359993 | 0.91 | KDM4E (0.63) | KDM4ENPSR1MEN1CYP1A2CYP2C19 | |
| SCHEMBL7611663 | 0.85 | NPSR1 (0.68) | KDM4ENPSR1MEN1CYP1A2CYP2C19 | |
| SCHEMBL3159880 | 0.82 | P2RY1 (0.72) | KDM4ENPSR1MEN1CYP1A2CYP2C19 | |
| SCHEMBL7645488 | 0.82 | KDM4E (0.74) | KDM4ENPSR1MEN1CYP1A2CYP2C19 | |
| Diflufenican SCHEMBL29373740 | 0.81 | KMT2A (1.00) | KDM4ENPSR1MEN1CYP1A2CYP2C19 | |
| Diflufenican SCHEMBL29549369 | 0.81 | KMT2A (1.00) | KDM4ENPSR1MEN1CYP1A2CYP2C19 | |
| Diflufenican SCHEMBL8536896 | 0.81 | KMT2A (1.00) | KDM4ENPSR1MEN1CYP1A2CYP2C19 | |
| Diflufenican SCHEMBL22023 | 0.81 | KMT2A (1.00) | KDM4ENPSR1MEN1CYP1A2CYP2C19 | |
| SCHEMBL9364603 | 0.80 | TAS1R3 (0.56) | KDM4ENPSR1MEN1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467473-B1 | Herbicidal compounds | SHELL INT RESEARCH (NL) | 1994-10-05 | — | — | EP | disclosed |
| US-5304532-A | For preemergence or postemergence use | SHELL RESEARCH LIMITED | 1994-04-19 | — | — | US | disclosed |
| EP-0467473-A1 | Herbicidal compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-01-22 | — | — | EP | disclosed |