Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364774 | 1.00 | MAPT (0.56) | MAPTKDM4EALDH1A1SMN1; SMN2APP | |
| SCHEMBL9362086 | 0.94 | APP (0.59) | MAPTKDM4EALDH1A1SMN1; SMN2APP | |
| SCHEMBL9362093 | 0.94 | APP (0.59) | MAPTKDM4EALDH1A1SMN1; SMN2APP | |
| SCHEMBL9508065 | 0.86 | MCL1 (0.65) | MAPTKDM4EALDH1A1SMN1; SMN2APP | |
| SCHEMBL4479985 | 0.82 | MAPT (0.56) | MAPTKDM4EALDH1A1SMN1; SMN2APP | |
| SCHEMBL6029000 | 0.82 | MAPT (0.56) | MAPTKDM4EALDH1A1SMN1; SMN2APP | |
| SCHEMBL9365093 | 0.82 | MAOB (0.46) | MAPTKDM4EALDH1A1SMN1; SMN2MCL1 | |
| SCHEMBL6028998 | 0.82 | MAPT (0.56) | MAPTKDM4EALDH1A1SMN1; SMN2APP | |
| SCHEMBL9365096 | 0.82 | MAOB (0.46) | MAPTKDM4EALDH1A1SMN1; SMN2MCL1 | |
| SCHEMBL4479980 | 0.82 | MAPT (0.56) | MAPTKDM4EALDH1A1SMN1; SMN2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335641-B1 | Organic nonlinear optical substance | TEIJIN LTD (JP) | 1994-01-05 | — | — | EP | disclosed |
| US-5196147-A | Optical crystals | TEIJIN LIMITED (JP) | 1993-03-23 | — | — | US | disclosed |
| EP-0335641-A2 | Organic nonlinear optical substance | TEIJIN LIMITED (JP) | 1989-10-04 | — | — | EP | disclosed |