SCHEMBL9508065

SCHEMBL9508065

N#CC(=CC=Cc1ccc(C=CC=C(C#N)C(=O)O)cc1)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.65
LMNA P02545 2/20 0.58
KDM4E B2RXH2 2/20 0.58
ALDH1A1 P00352 2/20 0.58
HPGD P15428 2/20 0.58
HTT P42858 1/20 0.58
MAPT P10636 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
KMT2A Q03164 1/20 0.55
EGFR P00533 2/20 0.53
CISD1 Q9NZ45 1/20 0.53
SLC16A3 O15427 1/20 0.53
CYP3A4 P08684 1/20 0.53
SLC16A1 P53985 1/20 0.53
GPR35 Q9HC97 1/20 0.53
MAOB P27338 1/20 0.49
APP P05067 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15082 0.93 MCL1 (0.76) MCL1LMNAKDM4EALDH1A1HPGD
SCHEMBL15081 0.93 MCL1 (0.76) MCL1LMNAKDM4EALDH1A1HPGD
SCHEMBL8773598 0.93 MCL1 (0.76) MCL1LMNAKDM4EALDH1A1HPGD
SCHEMBL9361502 0.92 MCL1 (0.56) MCL1LMNAKDM4EALDH1A1HPGD
SCHEMBL9362402 0.92 MCL1 (0.60) MCL1LMNAKDM4EALDH1A1HPGD
SCHEMBL9361497 0.92 MCL1 (0.56) MCL1LMNAKDM4EALDH1A1HPGD
SCHEMBL9362397 0.92 MCL1 (0.60) MCL1LMNAKDM4EALDH1A1HPGD
Ammonia Solution, Strong SCHEMBL434911 0.91 MCL1 (0.73) MCL1LMNAKDM4EALDH1A1HPGD
SCHEMBL9365751 0.87 LMNA (0.55) MCL1LMNAKDM4EALDH1A1HPGD
SCHEMBL9365485 0.87 MCL1 (0.52) MCL1LMNAKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58099457-A None JP disclosed
EP-0205083-B1 IMAGE FORMING METHOD AND TRANSFER RECORDING MEDIUM THEREFOR CANON KABUSHIKI KAISHA (JP) 1993-09-01 EP disclosed
US-5015552-A Multilayer optical image recording process involving crosslinking, treatment with heat or light, transferring CANON KABUSHIKI KAISHA (JP) 1991-05-14 US disclosed
US-5005028-A Image forming method and transfer recording medium therefor CANON KABUSHIKI KAISHA (JP) 1991-04-02 US disclosed
EP-0205083-A2 Image forming method and transfer recording medium therefor CANON KABUSHIKI KAISHA (JP) 1986-12-17 EP disclosed
US-4495343-A Visible light-sensitive polyester polymer and visible light-sensitive resin composition containing said polymer TEIJIN LIMITED (JP) 1985-01-22 US disclosed
JP-S5899457-A PHENYLENEBIS(ALPHA-CYANOBUTADIENECARBOXYLIC ACID) OR ITS DERIVATIVE AND ITS PREPARATION TEIJIN LTD 1983-06-13 JP disclosed