Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365264 | 0.83 | TSHR (0.46) | KDM4EHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL9368705 | 0.82 | DAO (0.48) | ALDH1A1MAPTGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9364640 | 0.79 | DAO (0.39) | KDM4EGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL2802039 | 0.77 | B3GNT2 (0.52) | KDM4EHPGDALDH1A1KMT2AGRIA1 | |
| SCHEMBL23589295 | 0.76 | GRIN2D (0.69) | KDM4EHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL8145145 | 0.73 | DAO (0.70) | KDM4EMEN1KMT2ADAO | |
| SCHEMBL9364597 | 0.73 | DAO (0.70) | KDM4EHSD17B10ALDH1A1MAPTTSHR | |
| SCHEMBL9364598 | 0.73 | DAO (0.70) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9368648 | 0.73 | DAO (0.44) | HSD17B10ALDH1A1KMT2ADAO | |
| SCHEMBL2801209 | 0.72 | HDAC6 (0.42) | KDM4EALDH1A1MAPTPOLBDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377112-B1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-08-24 | — | — | EP | claimed |
| EP-0377112-B1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-08-24 | — | — | EP | disclosed |
| US-5061706-A | 2,3-QUINOXALINEDIONES FOR USE AS NEUROLEPTICS | NOVO NORDISK A/S (DK) | 1991-10-29 | — | — | US | disclosed |
| EP-0377112-A1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1990-07-11 | — | — | EP | disclosed |