Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.39 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368705 | 0.82 | DAO (0.48) | DAOPARP1GRIA1GRIA2GRIA3 | |
| SCHEMBL9364786 | 0.79 | KDM4E (0.51) | DAOGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9365531 | 0.79 | FASN (0.44) | DAO | |
| SCHEMBL9365264 | 0.75 | TSHR (0.46) | DAOPARP1KDM4E | |
| SCHEMBL9368648 | 0.73 | DAO (0.44) | DAO | |
| SCHEMBL9364597 | 0.73 | DAO (0.70) | DAOKDM4E | |
| SCHEMBL8145145 | 0.73 | DAO (0.70) | DAOKDM4E | |
| SCHEMBL9364598 | 0.73 | DAO (0.70) | DAOPARP1 | |
| SCHEMBL9364584 | 0.72 | GRIA1 (0.41) | DAOGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL2802039 | 0.71 | B3GNT2 (0.52) | DAOPARP1GRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377112-B1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-08-24 | — | — | EP | claimed |
| EP-0377112-B1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-08-24 | — | — | EP | disclosed |
| US-5061706-A | 2,3-QUINOXALINEDIONES FOR USE AS NEUROLEPTICS | NOVO NORDISK A/S (DK) | 1991-10-29 | — | — | US | disclosed |
| EP-0377112-A1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1990-07-11 | — | — | EP | disclosed |