Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 8/20 | 0.70 |
| ▸ | FEN1 | P39748 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | DDO | Q99489 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 3/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8138622 | 0.86 | DAO (0.70) | DAOFEN1KDM4EOPRM1OPRL1 | |
| SCHEMBL9368648 | 0.79 | DAO (0.44) | DAOKMT2A | |
| SCHEMBL9364597 | 0.79 | DAO (0.70) | DAOKDM4EDDO | |
| SCHEMBL9364598 | 0.79 | DAO (0.70) | DAO | |
| SCHEMBL30770202 | 0.79 | GRIA1 (0.56) | DAOFEN1KDM4EOPRM1OPRL1 | |
| SCHEMBL9080167 | 0.79 | CA12 (0.52) | DAOKDM4EMPOMEN1KMT2A | |
| SCHEMBL26092144 | 0.77 | OPRM1 (0.50) | DAOFEN1KDM4EOPRM1OPRL1 | |
| SCHEMBL2802039 | 0.77 | B3GNT2 (0.52) | DAOKDM4EKMT2A | |
| SCHEMBL30910120 | 0.77 | OPRM1 (0.50) | DAOFEN1KDM4EOPRM1OPRL1 | |
| SCHEMBL9601771 | 0.76 | PGR (0.57) | DAOFEN1KDM4EOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556393-B1 | FUSED PYRAZINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 2000-07-26 | — | — | EP | disclosed |
| US-5283244-A | Anticonvulsants, nervous system disorders | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1994-02-01 | — | — | US | disclosed |
| EP-0556393-A1 | FUSED PYRAZINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-08-25 | — | — | EP | disclosed |