Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | CCR6 | P51684 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | FBP1 | P09467 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17397039 | 1.00 | KDM4E (0.67) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL9364793 | 1.00 | KDM4E (0.67) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL17397040 | 1.00 | KDM4E (0.67) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL8543761 | 0.87 | MAPT (0.70) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL8543768 | 0.87 | MAPT (0.70) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL21457626 | 0.84 | ALDH1A1 (0.76) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL21457622 | 0.84 | ALDH1A1 (0.76) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL4943479 | 0.82 | CYP1A2 (0.63) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL29894113 | 0.82 | CYP1A2 (0.63) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL9365674 | 0.82 | KDM4E (0.75) | KDM4EALDH1A1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016004272-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | PHARMACYCLICS LLC (US) | 2016-01-07 | — | — | WO | disclosed |
| EP-0335641-B1 | Organic nonlinear optical substance | TEIJIN LTD (JP) | 1994-01-05 | — | — | EP | disclosed |
| US-5196147-A | Optical crystals | TEIJIN LIMITED (JP) | 1993-03-23 | — | — | US | disclosed |
| EP-0335641-A2 | Organic nonlinear optical substance | TEIJIN LIMITED (JP) | 1989-10-04 | — | — | EP | disclosed |
| EP-0018682-A1 | Oxiranecarboxylic acid ester derivatives, their preparation and their inclusion in lipogenesis inhibiting compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-11-12 | — | — | EP | disclosed |