Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MASP2 | O00187 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364888 | 1.00 | MAPT (0.58) | MAPTLMNAPOLBKMT2AMEN1 | |
| SCHEMBL9361178 | 0.94 | MASP2 (0.55) | MAPTLMNAPOLBKMT2AMEN1 | |
| SCHEMBL9361183 | 0.94 | MASP2 (0.55) | MAPTLMNAPOLBKMT2AMEN1 | |
| SCHEMBL9116883 | 0.81 | KDM4E (0.64) | MAPTPOLBKMT2AMEN1GAA | |
| SCHEMBL9116880 | 0.81 | KDM4E (0.64) | MAPTPOLBKMT2AMEN1GAA | |
| SCHEMBL14680276 | 0.81 | MAPT (0.68) | MAPTLMNAPOLBKMT2AMEN1 | |
| SCHEMBL17131883 | 0.81 | MAPT (0.68) | MAPTLMNAPOLBKMT2AMEN1 | |
| SCHEMBL17466009 | 0.80 | POLB (0.73) | MAPTLMNAPOLBKMT2AMEN1 | |
| SCHEMBL7536662 | 0.79 | MAPT (0.67) | MAPTPOLBKMT2AMEN1GAA | |
| SCHEMBL7536666 | 0.79 | MAPT (0.67) | MAPTPOLBKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335641-B1 | Organic nonlinear optical substance | TEIJIN LTD (JP) | 1994-01-05 | — | — | EP | disclosed |
| US-5196147-A | Optical crystals | TEIJIN LIMITED (JP) | 1993-03-23 | — | — | US | disclosed |
| EP-0335641-A2 | Organic nonlinear optical substance | TEIJIN LIMITED (JP) | 1989-10-04 | — | — | EP | disclosed |