SCHEMBL936493

SCHEMBL936493

CCCCCCCCCCCCCCCC[C](CCCCCCCCCCCCCCCC)CCCCCCCCCCCCCCCC

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.58
CES1 P23141 4/20 0.58
TSHR P16473 5/20 0.57
THRB P10828 1/20 0.57
GPR84 Q9NQS5 7/20 0.55
PPARG P37231 7/20 0.55
PPARD Q03181 7/20 0.55
PPARA Q07869 7/20 0.55
HDAC11 Q96DB2 5/20 0.55
PTPN1 P18031 3/20 0.55
ALDH1A1 P00352 2/20 0.55
TLR2 O60603 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
FABP4 P15090 2/20 0.55
SLC22A6 Q4U2R8 1/20 0.55
SLC22A8 Q8TCC7 1/20 0.55
MEN1 O00255 1/20 0.55
ESR1 P03372 1/20 0.55
ALOX15 P16050 1/20 0.55
PDE4A P27815 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5394178 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL9284134 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL1982513 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL6046243 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL11314393 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL7211309 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL17842045 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL7627142 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL221255 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84
SCHEMBL11797136 1.00 CES2 (0.58) CES2CES1TSHRTHRBGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2470160-A2 USE OF AT LEAST ONE NUCLEIC ACID TO INFLUENCE THE NATURAL PIGMENTATION PROCESS Henkel AG & Co. KGaA (DE) 2012-07-04 EP disclosed
WO-2011009756-A2 USE OF AT LEAST ONE NUCLEIC ACID TO INFLUENCE THE NATURAL PIGMENTATION PROCESS HENKEL AG & CO. KGAA (DE) 2011-01-27 WO disclosed
WO-2010130510-A2 HAIR SHAPING PRODUCT CONTAINING ACETYLPYRIDINIUM SALTS HENKEL AG & CO. KGAA (DE) 2010-11-18 WO disclosed
US-20060073110-A1 High DS cationic polygalactomannan for skincare products ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC 2006-04-06 US disclosed
WO-2005016329-A1 TOPICAL COMPOSITIONS OF UREA AND AMMONIUM LACTATE AGIS INDUSTRIES (1983) LTD. (IL) 2005-02-24 WO disclosed
EP-1326577-A2 NOVEL USE OF SHORT-CHAINED CARBOXYLIC ACIDS Henkel Kommanditgesellschaft auf Aktien (DE) 2003-07-16 EP disclosed
WO-2002032383-A2 NOVEL USE OF SHORT-CHAINED CARBOXYLIC ACIDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-04-25 WO disclosed
EP-1014936-A1 EXTRACT AND COSMETIC PREPARATION Henkel Kommanditgesellschaft auf Aktien (DE) 2000-07-05 EP disclosed
WO-1999015145-A1 EXTRACT AND COSMETIC PREPARATION HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-04-01 WO disclosed
CN-1130862-A High lathering anti-dandruff shampoos with improved deposition of particulate anti-dandruff agent PROCTER & GAMBLE (US) 1996-09-11 CN disclosed
WO-1994026236-A1 HAIR-TREATMENT AGENTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1994-11-24 WO disclosed
WO-1993021896-A1 PERMANENT WAVING PROCESS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1993-11-11 WO disclosed