Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.57 |
| ▸ | ACE | P12821 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ECE1 | P42892 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CPA1 | P15085 | 2/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.50 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365219 | 1.00 | MME (0.57) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL9365243 | 1.00 | MME (0.57) | MMEACEALDH1A1HPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL8692953 | 0.98 | MME (0.56) | MMEACEALDH1A1HPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL8693014 | 0.98 | MME (0.56) | MMEACEALDH1A1HPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL8693006 | 0.98 | MME (0.56) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL10947257 | 0.87 | ACE (0.62) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL391211 | 0.85 | ACE (0.59) | MMEACENAALAD2 | |
| SCHEMBL5603448 | 0.85 | ACE (0.59) | MMEACENAALAD2 | |
| SCHEMBL650610 | 0.85 | ACE (0.59) | MMEACENAALAD2 | |
| SCHEMBL9068541 | 0.85 | MME (0.70) | MMEACECPA1ACE2NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419327-B1 | Amino acid derivatives, method for their preparation and their therapeutic application | BIOPROJET SOC CIV (FR) | 1994-07-27 | — | — | EP | claimed |
| WO-1991004246-A1 | METHOD FOR PREPARING AMINO ACID DERIVATIVES AND THERAPEUTICAL APPLICATIONS OF SAME | SOCIETE CIVILE BIOPROJET (FR) | 1991-04-04 | — | — | WO | claimed |
| EP-0419327-A1 | Amino acid derivatives, method for their preparation and their therapeutic application | SOCIETE CIVILE BIOPROJET (FR) | 1991-03-27 | — | — | EP | claimed |
| EP-0419327-B1 | Amino acid derivatives, method for their preparation and their therapeutic application | BIOPROJET SOC CIV (FR) | 1994-07-27 | — | — | EP | disclosed |
| WO-1991004246-A1 | METHOD FOR PREPARING AMINO ACID DERIVATIVES AND THERAPEUTICAL APPLICATIONS OF SAME | SOCIETE CIVILE BIOPROJET (FR) | 1991-04-04 | — | — | WO | disclosed |
| EP-0419327-A1 | Amino acid derivatives, method for their preparation and their therapeutic application | SOCIETE CIVILE BIOPROJET (FR) | 1991-03-27 | — | — | EP | disclosed |