Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365752 | 1.00 | LMNA (0.55) | LMNAKDM4EALDH1A1HPGDHTT | |
| SCHEMBL9360835 | 0.94 | APP (0.56) | LMNAKDM4EALDH1A1HPGDHTT | |
| SCHEMBL9360827 | 0.94 | APP (0.56) | LMNAKDM4EALDH1A1HPGDHTT | |
| SCHEMBL9508065 | 0.87 | MCL1 (0.65) | LMNAKDM4EALDH1A1HPGDHTT | |
| SCHEMBL9361771 | 0.86 | LMNA (0.59) | LMNAKDM4EALDH1A1HPGDHTT | |
| SCHEMBL9361768 | 0.86 | LMNA (0.59) | LMNAKDM4EALDH1A1HPGDHTT | |
| SCHEMBL9360876 | 0.85 | LMNA (0.55) | LMNAKDM4EALDH1A1HPGDHTT | |
| SCHEMBL9361502 | 0.83 | MCL1 (0.56) | LMNAKDM4EALDH1A1HPGDHTT | |
| SCHEMBL9361497 | 0.83 | MCL1 (0.56) | LMNAKDM4EALDH1A1HPGDHTT | |
| SCHEMBL9362098 | 0.82 | LMNA (0.55) | LMNAKDM4EALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335641-B1 | Organic nonlinear optical substance | TEIJIN LTD (JP) | 1994-01-05 | — | — | EP | disclosed |
| US-5196147-A | Optical crystals | TEIJIN LIMITED (JP) | 1993-03-23 | — | — | US | disclosed |
| EP-0335641-A2 | Organic nonlinear optical substance | TEIJIN LIMITED (JP) | 1989-10-04 | — | — | EP | disclosed |