⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12651664 | 0.83 | ALDH1A1 (0.38) | — | |
| SCHEMBL6110192 | 0.79 | — | — | |
| SCHEMBL572460 | 0.77 | — | — | |
| SCHEMBL5235261 | 0.73 | ADH1C (0.36) | — | |
| SCHEMBL27689613 | 0.69 | — | — | |
| SCHEMBL4579062 | 0.69 | — | — | |
| SCHEMBL23229179 | 0.69 | — | — | |
| SCHEMBL28829 | 0.67 | — | — | |
| SCHEMBL5522835 | 0.67 | — | — | |
| Dimethylformamide SCHEMBL28338245 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4636486-B2 | — | — | 2011-02-23 | — | — | JP | claimed |
| US-20080227828-A1 | Aryl Ureas With Angiogenisis Inhibiting Activity | BAYER HEALTHCARE LLC | 2008-09-18 | — | — | US | claimed |
| EP-1478358-A1 | ARYL UREAS WITH ANGIOGENESIS INHIBITING ACTIVITY | Bayer Pharmaceuticals Corporation (US) | 2004-11-24 | — | — | EP | claimed |
| US-20030207870-A1 | Aryl ureas with angiogenisis inhibiting activity | BAYER CORPORATION | 2003-11-06 | — | — | US | claimed |
| WO-2003068228-A1 | ARYL UREAS WITH ANGIOGENESIS INHIBITING ACTIVITY | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-08-21 | — | — | WO | claimed |
| WO-2000044216-A2 | GAMBOGIC ACID, ANALOGS AND DERIVATIVES AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS | CYTOVIA INC (US) | 2000-08-03 | — | — | WO | claimed |
| EP-0078478-B1 | HIGH-FREQUENCY WELDABLE POLYURETHANE FOAMS, AND PROCESS FOR PREPARING THE SAME | BAYER AG (DE) | 1986-05-21 | — | — | EP | claimed |
| US-10653684-B2 | Aryl ureas with angiogenisis inhibiting activity | BAYER HEALTHCARE LLC (US) | 2020-05-19 | — | — | US | disclosed |
| US-20180296541-A9 | ARYL UREAS WITH ANGIOGENISIS INHIBITING ACTIVITY | BAYER HEALTHCARE LLC (US) | 2018-10-18 | — | — | US | disclosed |
| US-20160015697-A1 | ARYL UREAS WITH ANGIOGENISIS INHIBITING ACTIVITY | BAYER HEALTHCARE LLC (US) | 2016-01-21 | — | — | US | disclosed |
| US-8618141-B2 | Aryl ureas with angiogenesis inhibiting activity | BAYER HEALTHCARE LLC (US) | 2013-12-31 | — | — | US | disclosed |
| US-20120289552-A1 | ARYL UREAS WITH ANGIOGENESIS INHIBITING ACTIVITY | BAYER HEALTHCARE LLC (US) | 2012-11-15 | — | — | US | disclosed |
| US-8242147-B2 | Aryl ureas with angiogenisis inhibiting activity | BAYER HEALTHCARE LLC (US) | 2012-08-14 | — | — | US | disclosed |
| US-20030216396-A1 | Pyridine, quinoline, and isoquinoline N-oxides as kinase inhibitors | BAYER CORPORATION | 2003-11-20 | — | — | US | disclosed |
| US-20030207870-A1 | Aryl ureas with angiogenisis inhibiting activity | BAYER CORPORATION | 2003-11-06 | — | — | US | disclosed |
| WO-2003068229-A1 | PYRIDINE, QUINOLINE, AND ISOQUINOLINE N-OXIDES AS KINASE INHIBITORS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-08-21 | — | — | WO | disclosed |
| WO-2003068228-A1 | ARYL UREAS WITH ANGIOGENESIS INHIBITING ACTIVITY | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-08-21 | — | — | WO | disclosed |
| WO-2000044216-A2 | GAMBOGIC ACID, ANALOGS AND DERIVATIVES AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS | CYTOVIA INC (US) | 2000-08-03 | — | — | WO | disclosed |
| CN-1050122-C | Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them | KRAL THOMAE GMBH (DE) | 2000-03-08 | — | — | CN | disclosed |
| CN-1083812-A | Benzimidazoles contains the pharmaceutical composition of these compounds and their preparation | KRAL THOMAE GMBH (DE) | 1994-03-16 | — | — | CN | disclosed |