Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9661099 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDRAB9AATM | |
| SCHEMBL9366237 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDRAB9AATM | |
| SCHEMBL9661078 | 0.89 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDATMTDP1 | |
| SCHEMBL9366142 | 0.89 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDATMTDP1 | |
| SCHEMBL9366328 | 0.89 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDATMTDP1 | |
| SCHEMBL9366145 | 0.89 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDATMTDP1 | |
| SCHEMBL9366319 | 0.89 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDATMTDP1 | |
| SCHEMBL9204236 | 0.86 | RAB9A (0.40) | ALDH1A1MAPTHPGDRAB9AATM | |
| SCHEMBL9202630 | 0.86 | RAB9A (0.40) | ALDH1A1MAPTHPGDRAB9AATM | |
| SCHEMBL9728199 | 0.86 | RAB9A (0.40) | ALDH1A1MAPTHPGDRAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435320-B1 | 2(2-Cyclopropylpyrrolidin-4-ylthio)-carbapenem derivatives | BANYU PHARMA CO LTD (JP) | 1994-10-05 | — | — | EP | disclosed |
| US-5112818-A | Antibiotics and bactericides | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0435320-A1 | 2(2-Cyclopropylpyrrolidin-4-ylthio)-carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-07-03 | — | — | EP | disclosed |