Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.34 |
| ▸ | PPARA | Q07869 | 5/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366264 | 1.00 | PPARG (0.34) | PPARGPPARANR1H4ALDH1A1HSD17B10 | |
| SCHEMBL9366188 | 0.93 | HSD17B10 (0.34) | PPARGPPARANR1H4ALDH1A1HSD17B10 | |
| SCHEMBL9366193 | 0.93 | HSD17B10 (0.34) | PPARGPPARANR1H4ALDH1A1HSD17B10 | |
| SCHEMBL9365145 | 0.90 | ALDH1A1 (0.34) | PPARGPPARANR1H4ALDH1A1HSD17B10 | |
| SCHEMBL9365153 | 0.90 | ALDH1A1 (0.34) | PPARGPPARANR1H4ALDH1A1HSD17B10 | |
| SCHEMBL9365795 | 0.90 | ALDH1A1 (0.43) | PPARGPPARANR1H4ALDH1A1SIRT5 | |
| SCHEMBL9365802 | 0.90 | ALDH1A1 (0.43) | PPARGPPARANR1H4ALDH1A1SIRT5 | |
| SCHEMBL9361195 | 0.89 | PPARG (0.40) | PPARGPPARAALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL9361202 | 0.89 | PPARG (0.40) | PPARGPPARAALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL9360593 | 0.88 | HSD17B10 (0.36) | PPARGPPARANR1H4ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418038-B1 | Naphthalene derivative and preparation method thereof | TEIJIN LTD (JP) | 1994-04-20 | — | — | EP | disclosed |
| US-5149859-A | Cardiovascular disorders | TEIJIN LIMITED (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0418038-A1 | Naphthalene derivative and preparation method thereof | TEIJIN LIMITED (JP) | 1991-03-20 | — | — | EP | disclosed |