Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 7/20 | 0.35 |
| ▸ | PPARA | Q07869 | 7/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9361205 | 0.93 | HSD17B10 (0.38) | HSD17B10TSHRCYP3A4ALOX15HIF1A | |
| SCHEMBL9364858 | 0.89 | ALDH1A1 (0.47) | ALDH1A1PPARGPPARAALOX5NR1H4 | |
| SCHEMBL9365145 | 0.89 | ALDH1A1 (0.34) | HSD17B10TSHRCYP3A4ALOX15HIF1A | |
| SCHEMBL9365153 | 0.89 | ALDH1A1 (0.34) | HSD17B10TSHRCYP3A4ALOX15HIF1A | |
| SCHEMBL9366309 | 0.88 | ALOX5 (0.43) | HSD17B10TSHRCYP3A4ALDH1A1PPARG | |
| SCHEMBL9366264 | 0.88 | PPARG (0.34) | HSD17B10TSHRCYP3A4ALOX15HIF1A | |
| SCHEMBL9366259 | 0.88 | PPARG (0.34) | HSD17B10TSHRCYP3A4ALOX15HIF1A | |
| SCHEMBL9365320 | 0.85 | HSD17B10 (0.40) | HSD17B10TSHRCYP3A4ALOX15HIF1A | |
| SCHEMBL9365053 | 0.81 | EPHX1 (0.46) | ALDH1A1PPARGPPARANR1H4SIRT5 | |
| SCHEMBL9360831 | 0.81 | HSD17B10 (0.35) | HSD17B10TSHRCYP3A4ALOX15HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418038-B1 | Naphthalene derivative and preparation method thereof | TEIJIN LTD (JP) | 1994-04-20 | — | — | EP | disclosed |
| US-5149859-A | Cardiovascular disorders | TEIJIN LIMITED (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0418038-A1 | Naphthalene derivative and preparation method thereof | TEIJIN LIMITED (JP) | 1991-03-20 | — | — | EP | disclosed |