Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.45 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.45 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.45 |
| ▸ | PPOX | P50336 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366509 | 0.92 | GAA (0.45) | TDP1CYP3A4ALDH1A1HPGDALOX15 | |
| SCHEMBL9370601 | 0.87 | MEN1 (0.49) | TDP1PPOXMEN1KMT2ANR1I2 | |
| SCHEMBL10930233 | 0.76 | PPOX (0.59) | TDP1PPOXMEN1KMT2ANR1I2 | |
| SCHEMBL6980225 | 0.75 | PPOX (0.42) | TDP1PPOXMEN1KMT2ANR1I2 | |
| SCHEMBL9366762 | 0.75 | GABRB3 (0.48) | GABRA2GABRB2MAPTGABRPGABRD | |
| SCHEMBL9366995 | 0.74 | GABRB3 (0.42) | GABRA2GABRB2MAPTGABRPGABRD | |
| SCHEMBL6976022 | 0.73 | PPOX (0.40) | TDP1PPOXMEN1KMT2ANR1I2 | |
| SCHEMBL11545287 | 0.73 | MEN1 (0.47) | TDP1ALDH1A1PPOXMEN1KMT2A | |
| SCHEMBL9666543 | 0.72 | CYP3A4 (0.43) | TDP1CYP3A4ALDH1A1HPGDALOX15 | |
| SCHEMBL9366887 | 0.71 | GABRB3 (0.42) | GABRA2GABRB2MAPTGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435616-B1 | An oxadiazolinone derivative and its production and use | SUMITOMO CHEMICAL CO (JP) | 1994-12-28 | — | — | EP | claimed |
| US-5124341-A | Insecticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-06-23 | — | — | US | claimed |
| EP-0435616-A2 | An oxadiazolinone derivative and its production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-07-03 | — | — | EP | claimed |