Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 3/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.67 |
| ▸ | IDO1 | P14902 | 9/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.64 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.64 |
| ▸ | DRD2 | P14416 | 4/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.64 |
| ▸ | FYN | P06241 | 3/20 | 0.64 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11617815 | 0.98 | ADRA2C (0.74) | ADRA2CCYP2C9CYP3A4IDO1CYP1A2 | |
| SCHEMBL11304305 | 0.89 | ADRA2C (0.74) | ADRA2CCYP2C9CYP3A4IDO1CYP1A2 | |
| SCHEMBL31180917 | 0.87 | ADRA2C (0.71) | ADRA2CCYP2C9CYP3A4IDO1CYP1A2 | |
| SCHEMBL11611712 | 0.87 | ADRA2C (0.71) | ADRA2CCYP2C9CYP3A4IDO1CYP1A2 | |
| SCHEMBL29846165 | 0.87 | ADRA2C (1.00) | ADRA2CCYP2C9CYP3A4IDO1CYP1A2 | |
| SCHEMBL6305674 | 0.87 | ADRA2C (0.71) | ADRA2CCYP2C9CYP3A4IDO1CYP1A2 | |
| SCHEMBL4664253 | 0.87 | ADRA2C (1.00) | ADRA2CCYP2C9CYP3A4IDO1CYP1A2 | |
| SCHEMBL4817509 | 0.87 | ADRA2C (1.00) | ADRA2CCYP2C9CYP3A4IDO1CYP1A2 | |
| SCHEMBL6393853 | 0.87 | ADRA2C (0.71) | ADRA2CCYP2C9CYP3A4IDO1CYP1A2 | |
| SCHEMBL30256070 | 0.87 | ADRA2C (1.00) | ADRA2CCYP2C9CYP3A4IDO1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427242-B1 | Azole derivatives and antifungal drugs containing the same as an active component | KAO CORP (JP) | 1994-09-21 | — | — | EP | disclosed |
| EP-0188383-B1 | Imidazole derivatives, their preparation and therapeutic use | SANKYO CO (JP) | 1994-04-27 | — | — | EP | disclosed |
| US-5183824-A | Azole derivatives and antifungal drugs containing the same as an active component | KAO CORPORATION (JP) | 1993-02-02 | — | — | US | disclosed |
| US-5110826-A | AZOLE DERIVATIVES AND ANTIFUNGAL DRUGS CONTAINING THE SAME AS AN ACTIVE COMPONENT | KAO CORPORATION (JP) | 1992-05-05 | — | — | US | disclosed |
| EP-0427242-A1 | Azole derivatives and antifungal drugs containing the same as an active component | KAO CORPORATION (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4894385-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1990-01-16 | — | — | US | disclosed |
| EP-0188383-A2 | Imidazole derivatives, their preparation and therapeutic use | SANKYO COMPANY LIMITED (JP) | 1986-07-23 | — | — | EP | disclosed |
| US-4177350-A | FUNGICIDES | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1979-12-04 | — | — | US | disclosed |
| US-4131608-A | Thioethers | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1978-12-26 | — | — | US | disclosed |
| US-4107314-A | Antifungal thio-alkyl-imidazole derivatives | PFEIZER INC. (US) | 1978-08-15 | — | — | US | disclosed |
| US-4055652-A | 1-[β(R-thio)phenethyl]imidazoles and derivatives thereof | SYNTEX (U.S.A.) INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-4012566-A | CONTACTING WITH A HOMOGENEOUS OLEFIN DISPROPORTIONATION CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1977-03-15 | — | — | US | disclosed |
| US-3995095-A | Modification of polymers by treatment with olefins | PHILLIPS PETROLEUM COMPANY (US) | 1976-11-30 | — | — | US | disclosed |