Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8742253 | 0.99 | PPARG (0.53) | PPARGPPARAMEN1KMT2AKDM4E | |
| SCHEMBL4588155 | 0.91 | PPARG (0.51) | PPARGPPARAMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL8742634 | 0.91 | PPARG (0.50) | PPARGPPARAMEN1KMT2AKDM4E | |
| SCHEMBL4588915 | 0.90 | PPARG (0.55) | PPARGPPARAMEN1KMT2AHTR7 | |
| Xaliproden SCHEMBL137094 | 0.89 | SIGMAR1 (0.51) | PPARGPPARAMEN1KMT2AKDM4E | |
| Xaliproden SCHEMBL29377982 | 0.89 | SIGMAR1 (0.51) | PPARGPPARAMEN1KMT2AKDM4E | |
| SCHEMBL9366593 | 0.88 | PPARG (0.51) | PPARGPPARAMEN1KMT2AKDM4E | |
| SCHEMBL6589155 | 0.88 | PPARG (0.50) | PPARGPPARAMEN1KMT2AKDM4E | |
| Xaliproden SCHEMBL29393004 | 0.88 | SIGMAR1 (0.50) | PPARGPPARAMEN1KMT2AKDM4E | |
| Xaliproden SCHEMBL116721 | 0.88 | SIGMAR1 (0.50) | PPARGPPARAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458697-B1 | N-substituted trifluoromethylphenyl tetrahydropyridines, process for their preparation, intermediates and pharmaceutical preparations containing them | SANOFI ELF (FR) | 1994-07-27 | — | — | EP | disclosed |
| EP-0458697-A1 | N-substituted trifluoromethylphenyl tetrahydropyridines, process for their preparation, intermediates and pharmaceutical preparations containing them | ELF SANOFI (FR) | 1991-11-27 | — | — | EP | disclosed |