Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366482 | 1.00 | LMNA (0.52) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9366481 | 1.00 | LMNA (0.52) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9365679 | 0.92 | LMNA (0.53) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9365675 | 0.92 | LMNA (0.53) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9365390 | 0.91 | LMNA (0.48) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9365487 | 0.91 | KMT2A (0.48) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9365482 | 0.91 | KMT2A (0.48) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9365498 | 0.91 | LMNA (0.48) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9366552 | 0.91 | ALDH1A1 (0.48) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9366555 | 0.91 | ALDH1A1 (0.48) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | claimed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | claimed |
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |