Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369551 | 0.91 | SMN1; SMN2 (0.58) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9366734 | 0.87 | LMNA (0.54) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4429146 | 0.86 | LMNA (0.65) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9365789 | 0.83 | KMT2A (0.72) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL29624123 | 0.83 | KMT2A (0.72) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4429170 | 0.83 | LMNA (0.67) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8342323 | 0.81 | LMNA (0.72) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9366719 | 0.81 | LMNA (0.44) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9365734 | 0.80 | LMNA (0.45) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4422567 | 0.79 | LMNA (0.79) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | claimed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | claimed |
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |