Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 6/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369551 | 0.87 | SMN1; SMN2 (0.58) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9366700 | 0.87 | MEN1 (0.52) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL4429170 | 0.86 | LMNA (0.67) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9365765 | 0.84 | LMNA (0.44) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL4422567 | 0.82 | LMNA (0.79) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL4429146 | 0.82 | LMNA (0.65) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL29624123 | 0.81 | KMT2A (0.72) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9365789 | 0.81 | KMT2A (0.72) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9366719 | 0.81 | LMNA (0.44) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9366747 | 0.81 | SMN1; SMN2 (0.38) | LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | claimed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | claimed |
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |