Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28475922 | 0.98 | ITGB3 (0.33) | TSHRNFKB1CYP2C19ITGB3ITGA2B | |
| SCHEMBL10743893 | 0.82 | TSHR (0.37) | TSHRHDAC4HDAC6 | |
| SCHEMBL10444901 | 0.82 | KDM4E (0.37) | TSHRNFKB1CYP2C19ITGB3ITGA2B | |
| SCHEMBL9301408 | 0.81 | MEN1 (0.38) | HDAC4HDAC6 | |
| SCHEMBL10740515 | 0.78 | KMT2A (0.32) | TSHR | |
| SCHEMBL536355 | 0.78 | — | — | |
| SCHEMBL11098530 | 0.77 | DPP4 (0.47) | TSHRALDH1A1 | |
| SCHEMBL11027281 | 0.76 | HDAC4 (0.30) | HDAC4HDAC6 | |
| SCHEMBL9198978 | 0.76 | EZH2 (0.45) | TSHRALDH1A1 | |
| SCHEMBL28889135 | 0.75 | HDAC4 (0.39) | TSHRNFKB1CYP2C19HDAC4HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314472-B1 | Novel piperidyl-triazine derivatives and their use as polymer stabilizers | SANKYO CO (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0373892-A1 | Tetramethyl piperidyl terminated triazine oligomeric esters and amides | ICI AMERICAS INC. (US) | 1990-06-20 | — | — | EP | disclosed |
| US-4889882-A | RADIATION RESISTANCE, PHOTOSTABILITY POLYMER ADDITIVE | ICI AMERICAS INC. (US) | 1989-12-26 | — | — | US | disclosed |
| EP-0314472-A2 | Novel piperidyl-triazine derivatives and their use as polymer stabilizers | Sankyo Company Limited (JP) | 1989-05-03 | — | — | EP | disclosed |